Echinacea plants may aid in the treatment of common skin issues, according to research. In a test-tube experiment, researchers discovered that the anti-inflammatory and antibacterial characteristics of echinacea inhibited the growth of Propionibacterium, a common acne-causing bacteria ( 22 ).
Adult
Take echinacea three times daily for the first ten days of a cold, flu, upper respiratory infection, or bladder infection to stimulate the immune system generally.
Echinacea should NOT be taken on an empty stomach. Take it with food or a big glass of water instead.
In whom should echinacea not be taken?
Consult your doctor before using echinacea if you regularly take other medications. Additionally, if you smoke, use illegal substances, drink alcohol or caffeine-containing beverages, you should disclose this to your doctor. These might impact how echinacea functions.
If you have an autoimmune ailment (like lupus), an infection with the human immunodeficiency virus (HIV), or acquired immunodeficiency syndrome, echinacea may not be beneficial to you (AIDS). Before beginning to use echinacea, you should discuss with your doctor if you are pregnant or nursing.
Echinacea allergy risk may be increased if you have a history of allergies to daisies, ragweed, marigolds, chrysanthemums, or other related plants.
What benefits does echinacea provide the body?
Echinacea may boost your immune system, enabling you to combat viral or bacterial colds and flu. According to certain studies, the echinacea plant includes compounds that aid in the production of white blood cells by your body. These white blood cells function as part of your immune system to combat infection when your upper respiratory tract (nose, mouth, and throat) becomes infected.
But a 2014 research that examined two dozen additional studies discovered only flimsy proof that echinacea supplements actually work to treat colds. Echinacea may help treat colds, but it has not been demonstrated to hasten the onset of a cold.
Several different infections may be repelled by echinacea. According to some research, echinacea helps treat ear infections, urinary tract infections, and slow-healing cuts and wounds. Even though echinacea can occasionally assist with small illnesses, if the issue persists, you should visit a doctor.
Possibly Effective for…
- Typical cold Numerous studies in the scientific community have demonstrated that consuming some echinacea products when cold symptoms first appear will slightly lessen symptoms in adults. However, more research demonstrates no benefit. The issue is that several echinacea plant varieties and processing techniques have been utilized in scientific investigations. It is not unexpected that different studies provide varied outcomes because the studies have not been consistent. The advantage will probably be minimal at best if it aids with COLD TREATMENT. There is conflicting evidence on echinacea’s ability to PREVENT the common cold. According to some studies, ingesting echinacea can cut your chance of getting a cold by 45 to 58 percent. However, some studies indicate that eating echinacea while you are exposed to cold viruses does not shield you from getting the common cold.
Insufficient Evidence to Rate Effectiveness for…
- Anxiety. According to preliminary studies, consuming 40 mg of a specific echinacea extract (ExtractumPharma ZRT, Budapest, Hungary) every day for seven days can help people feel less anxious. However, taking less than 40 mg a day does not seem to work.
- execution of an exercise. Echinacea (Puritian’s Pride, Oakdale, NY) four times daily for 28 days enhances healthy men’s oxygen intake during exercise testing, according to preliminary studies.
- Gingivitis. A mouthwash with echinacea, gotu kola, and elderberry (HM-302, Izum Pharmaceuticals, New York, NY) may help prevent gum disease from getting worse by using it three times a day for 14 days. This is according to preliminary studies. Although it is not always helpful, applying a particular mouth patch made of the same components (PerioPatch, Izun Pharmaceuticals, New York, NY) appears to lessen some gum disease symptoms.
- Virus of Herpes Simplex (HSV). Uncertainty exists over the effectiveness of echinacea in the treatment of HSV. A Vogel Bioforce AG’s Echinaforce, 800 mg twice day for six months, according to some research, does not appear to prevent or shorten the frequency or duration of recurrent genital herpes. However, additional studies demonstrate that most persons with cold sores have less itching, tension, and discomfort while using a combination medication containing echinacea (Esberitox, Schaper & Brummer, Salzgitter-Ringelheim, Germany) (herpes labialis).
- Papilloma virus in humans (HPV). According to preliminary studies, taking a combination supplement called Immune Act, manufactured by Erba Vita SpA in Republica San Marino, Italy, daily for a month can help prevent anal warts from returning in persons who have had them surgically removed. The conclusions of this study, however, are suspect due to its low quality.
- Influenza (flu). According to preliminary studies, taking a specialized echinacea supplement, such as Monoselect Echinacea from PharmExtracta in Pontenure, Italy, daily for 15 days may help persons with breathing issues like bronchitis or asthma respond better to the flu vaccine.
- low level of white blood cells (Leukopenia). Early studies suggest that administering 50 drops of Esberitox N, Schaper & Brummer, Salzgitter-Ringelheim, Germany, between cycles of chemoradiotherapy can increase red and white blood cell counts in some women with advanced breast cancer. Esberitox N contains extracts of echinacea root, thuja leaf, and wild indigo. However, not all patients experience this effect, and dosages less than 50 drops don’t appear to be effective. Additionally, it doesn’t appear that this medicine lowers the risk of infection.
- infection in the middle ear. Early research indicates that giving children aged 1 to 5 who have a history of ear infections a specific liquid echinacea extract three times daily for three days at the first indication of the common cold does not prevent an ear infection. In fact, ear infections appeared to be rising.
- Tonsillitis. According to preliminary study, spraying a specific mixture of sage and echinacea into the mouth every two hours for up to ten times a day for up to five days alleviates sore throat sensations in a manner comparable to that of regularly used medication sprays for tonsillitis sufferers. Other preliminary studies indicate that giving persons with tonsillitis 50 drops of the echinacea supplement Esberitox, Schaper & Brummer, Salzgitter-Ringelheim, Germany, three times a day for two weeks, coupled with an antibiotic, can lessen painful throat and improve general wellbeing.
- eye irritation (Uveitis). Early research indicates that giving persons with eye inflammation 150 mg of an echinacea supplement (Iridium, SOOFT Italia SpA) twice day for four weeks along with eye drops and a steroid to treat inflammation does not enhance vision any more than giving them eye drops and steroids alone does.
- Warts. According to preliminary study, consuming echinacea orally every day for up to three months won’t get rid of warts on the skin. However, utilizing traditional treatments along with a supplement containing echinacea, methionine, zinc, probiotics, antioxidants, and substances that boost the immune system for six months appears to be more effective than using conventional treatments only.
- infections of the urinary tract (UTIs).
- Candida infections.
- HIV/AIDS.
- infections of the bloodstream.
- Staph infections.
- Syphilis.
- Typhoid.
- Malaria.
- Diphtheria.
- head pain from migraines.
- syndrome of protracted weariness (CFS).
- Eczema.
- other allergens, such as hay fever.
- Stinging bees.
- Hyperactive/attentional deficit disorder (ADHD).
- Swine flu
- arthritis rheumatoid (RA).
- Indigestion.
- Pain.
- Dizziness.
- Snake bites are common.
- other circumstances
According to the following scale, the effectiveness of natural medicines is rated by Natural Medicines Comprehensive Database: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
Side Effects
When used orally for a brief period of time, echinacea is LIKELY SAFE for the majority of people. Echinacea has been used safely in a variety of liquid and solid formulations for up to 10 days. A. Vogel Bioforce AG, Switzerland’s Echinaforce is one of many products that can be used safely for up to six months.
Fever, nausea, vomiting, bad taste, stomach discomfort, diarrhea, sore throat, dry mouth, headache, numb tongue, dizziness, sleeplessness, confusion, and joint and muscle aches are a some of the side effects that have been noted. Echinacea has been known to occasionally result in liver irritation.
Children and adults who are allergic to ragweed, mums, marigolds, or daisies are most likely to experience allergic responses when using echinacea. Before using echinacea, make sure to see your doctor if you have any allergies.
Brief overview
However, no studies utilizing Echinacea in the prevention or treatment of illnesses similar to COVID-19 have been found. Current research suggests that echinacea supplementation may reduce the duration and severity of acute respiratory tract infections. There were not many side events reported, indicating the relative safety of this herbal medication. Clinical studies have shown that Echinacea lowers levels of immunological molecules associated with cytokine storm, despite the fact that it might boost immune activity, which raises concerns that it can worsen over-activation of the immune system in cytokine storm.
Verdict
When given at the earliest sign of infection, Echinacea supplements may help with the symptoms of acute respiratory infections (ARI) and the common cold. No trials employing Echinacea in the prevention or treatment of illnesses like COVID-19, however, have been found. When taken at the outset of symptoms, Echinacea may lessen the intensity and/or duration of ARI, according to earlier research. E. purpurea or a mixture of E. purpurea and E. angustifolia having standardized levels of active components were employed in trials claiming benefit.
Echinacea use hasn’t been associated with many side effects, which suggests that this herbal remedy is generally harmless. No human studies using echinacea for up to 4 months could be found that showed cytokine storm symptoms.
The results were largely consistent with a reduction in the pro-inflammatory cytokines that are involved in the progression of cytokine storm and Acute Respiratory Distress Syndrome (ARDS), factors that are highly significant in the death of COVID-19 patients when looking at all human trials that reported changes in cytokine levels in response to Echinacea supplementation. Even though there isn’t any research on the therapeutic benefits of echinacea in the treatment of cytokine storms right now, this evidence shows that more study is necessary.
Can echinacea be taken with vitamin D?
Vitamin D3 and echinacea did not interact in any way. This does not imply that there are no interactions, though. Always get advice from your doctor.
What medicines and echinacea interact?
The purple coneflower is another name for the genus of native North American plants known as echinacea. An extract derived from the root of the herb Echinacea purpurea is the most popular herbal product in the country. Commercial echinacea preparations are often not standardized to any specific component because the plant’s active ingredient has not been discovered. The variability of the products utilized in different studies makes it challenging to evaluate the echinacea study literature. The herb is frequently used for this purpose and has been suggested as a preventative therapy for upper respiratory infections. However, it appears from the available research that taking preventive echinacea has little to no effect on the frequency, severity, or duration of upper respiratory infections. The evidence for treating upper respiratory infections seems to point to a slight favorable impact. Echinacea has not been associated with any significant herb-drug interactions, and the few and mild side effects that have been documented include nausea, dizziness, and gastrointestinal distress.
The purple coneflower is another name for the genus of plants known as echinacea, which are indigenous to the Midwest of North America. Three of the nine species of echinacea—Echinacea purpurea, Echinacea angustifolia, and Echinacea pallida—are used to make echinacea preparations. The preparation that is used the most frequently in this nation is a liquid extract prepared from E. purpurea root. There are many different trade names used to market echinacea.
Native Americans were the first to employ this plant medicinally, using E. angustifolia to cure everything from respiratory ailments to snakebites. Echinacea was employed as a blood purifier and a dizziness remedy during the 19th century. Up until the invention of current antibiotics, it was utilized as a cold and flu cure as well as an anti-infective. Echinacea is one of the top three plants sold in the US thanks to its recent revival as a remedy for upper respiratory infections (URIs). 1
Can echinacea harm the liver?
The more frequent echinacea adverse effects are as follows:
- headaches
- dizziness
- feeling unwell
- belly pain
- constipation
- skin repercussions (redness, itchiness and swelling)
- Children are more likely to have them.
Echinacea use for longer than 8 weeks at a time may cause liver damage or immune system suppression. If you are taking medications known to have an adverse effect on your liver, herbalists advise against taking echinacea.
If you use any additional medications, herbs, or supplements, check with your doctor first.
Using echinacea safely
If you want to substitute echinacea for your cancer therapy, let your doctor know. Additionally, if you are considering taking it concurrently with your cancer therapy.
In some people, it may not be safe to use in conjunction with other cancer treatments.
Echinacea may impair the effectiveness of some chemotherapy medications, including etoposide.
Sometimes pharmacists and medical professionals advise lymphoma patients not to consume echinacea. This is so that it won’t affect how they’re being treated.
Researchers discovered that echinacea and etravine were safe to ingest together in HIV-positive individuals.
If any of the following apply to you before consuming echinacea:
- are breastfeeding or pregnant
- have a medical condition like autoimmune illness, HIV, or AIDS that impairs your immune system
- are medicating to weaken your immune system because it might fight them
- are under 12 years old
- There is a possibility of allergic responses including skin rashes, according to the medical health regulatory association (MHRA).
Always discuss the use of complementary or alternative cancer therapy with your doctors and nurses. They could affect how well your other therapies work.
Your treatment team can point you in the direction of further resources if they don’t have the knowledge you need.
Is long-term echinacea use safe?
editor’s note Dr. Kligler’s review1 of echinacea was thorough, succinct, and effectively summed up the research supporting the well-known herb. 1 His review stated that the usage of echinacea has not been associated with any recognized medication interactions. Echinacea should not be used with other medications known to be hepatotoxic, such as amiodarone, methotrexate, and ketoconazole, even though there have been no reports of any significant drug interactions with echinacea. This is because it has been suggested that using echinacea for longer than eight weeks may cause hepatotoxicity. 2 Hepatotoxicity may become more common even when acetaminophen and echinacea are used together. 3 This is particularly crucial because acetaminophen and echinacea are regularly used to treat the cold’s symptoms.
Echinacea also has the ability to suppress the immune system when used for a prolonged period of time (greater than eight weeks), in contrast to the acute immunostimulatory effects of the herb.
4 This could be one reason why prior research on the use of echinacea for the prevention of colds failed to demonstrate any benefits, as most trials included patients who took the supplement for more than eight weeks.
Echinacea should, in my opinion, only be used for acute illnesses for a maximum of two weeks. I think it’s best to avoid using echinacea on a regular basis because it can increase the risk of hepatotoxicity, may have the ability to suppress the immune system, and hasn’t been proven to be effective in preventing colds. Despite the fact that there are no known pharmacological interactions with echinacea, we still need to keep a close eye out for any possible interactions and side effects.
In response, I concur with Dr. Chua that echinacea use for an extended period of time should be avoided because there is no proof that doing so prevents upper respiratory infections. But there isn’t enough proof to support the claim that echinacea causes liver damage. The presence of alkaloids in the pyrrolizidine family in specific portions of the echinacea plant gave rise to the first worries about hepatotoxicity with long-term usage of echinacea. Comfrey contains pyrrolizidine alkaloids, which are known to be hepatotoxic when used over an extended period of time. But isotussilagine and tussilagine, two pyrrolizidine alkaloids discovered in echinacea, have a saturated nucleus. 1 As of right now, there is no evidence that this group of pyrrolizidines is hepatotoxic. Therefore, I believe that Dr. Chua’s suggestion to avoid taking acetaminophen and echinacea together is not supported by the available research and may cause unjustified concerns for medical professionals and patients over the usage of this plant. It is also noteworthy that despite echinacea’s extensive use, there have been no reported cases of serious hepatotoxicity associated with it.