Furthermore, echinacea products frequently do not contain exactly what is stated on the label. According to one study, 10% of samples of echinacea products were devoid of any echinacea (32).
However, studies have shown that the following doses can help boost immunity (11):
- Three times a day, take 300–500 mg of dry powdered echinacea purpurea extract.
- 2.5 ml, three times per day, or up to 10 ml per day, for liquid extract tinctures.
However, it’s essential to adhere to the directions provided with your particular supplement.
The long-term effects of echinacea on the body are still mostly understood, so these suggestions are for short-term use only.
The wide range of echinacea products makes it challenging to establish a suggested dosage. Depending on the type of echinacea you’re using, the dosages change.
How to take Echinacea?
Use echinacea precisely as instructed on the label or as your doctor instructs. Never use more, less, or for a longer period of time than advised.
Consult your doctor before considering the usage of herbal supplements. You might also think about speaking with a doctor who specializes in the use of herbal remedies and dietary supplements.
If you decide to use echinacea, follow the instructions on the bottle or those provided by your physician, pharmacist, or other healthcare professional. Use only as much of this product as the label instructs.
At the earliest indication of a cold, echinacea is said to work best. Echinacea might lessen the severity of cold symptoms even if it may not be able to prevent a cold.
Echinacea topical (for the skin) shouldn’t be consumed orally. This product’s topical forms should only be applied to skin.
Echinacea should not be used concurrently in any form (tablets, liquid, tincture, teas, etc.) without consulting a doctor. Combining multiple formulas ups the likelihood of an overdose.
If the problem you are using echinacea to treat does not get better or if it worsens while taking this medication, contact your doctor right once.
Take the next dose as scheduled and skip the missed one. Never combine two dosages into one.
Adult
Take echinacea three times daily for the first ten days of a cold, flu, upper respiratory infection, or bladder infection to stimulate the immune system generally.
Echinacea should NOT be taken on an empty stomach. Take it with food or a big glass of water instead.
Why echinacea shouldn’t be taken?
Consult your doctor before using echinacea if you regularly take other medications. Additionally, if you smoke, use illegal substances, drink alcohol or caffeine-containing beverages, you should disclose this to your doctor. These might impact how echinacea functions.
If you have an autoimmune ailment (like lupus), an infection with the human immunodeficiency virus (HIV), or acquired immunodeficiency syndrome, echinacea may not be beneficial to you (AIDS). Before beginning to use echinacea, you should discuss with your doctor if you are pregnant or nursing.
Echinacea allergy risk may be increased if you have a history of allergies to daisies, ragweed, marigolds, chrysanthemums, or other related plants.
What affects the body does echinacea have?
Echinacea may boost your immune system, enabling you to combat viral or bacterial colds and flu. According to certain studies, the echinacea plant includes compounds that aid in the production of white blood cells by your body. These white blood cells function as part of your immune system to combat infection when your upper respiratory tract (nose, mouth, and throat) becomes infected.
But a 2014 research that examined two dozen additional studies discovered only flimsy proof that echinacea supplements actually work to treat colds. Echinacea may help treat colds, but it has not been demonstrated to hasten the onset of a cold.
Several different infections may be repelled by echinacea. According to some research, echinacea helps treat ear infections, urinary tract infections, and slow-healing cuts and wounds. Even though echinacea can occasionally assist with small illnesses, if the issue persists, you should visit a doctor.
Can echinacea harm the liver?
The more frequent echinacea adverse effects are as follows:
- headaches
- dizziness
- feeling unwell
- belly pain
- constipation
- skin repercussions (redness, itchiness and swelling)
- Children are more likely to have them.
Echinacea use for longer than 8 weeks at a time may cause liver damage or immune system suppression. If you are taking medications known to have an adverse effect on your liver, herbalists advise against taking echinacea.
If you use any additional medications, herbs, or supplements, check with your doctor first.
Using echinacea safely
If you want to substitute echinacea for your cancer therapy, let your doctor know. Additionally, if you are considering taking it concurrently with your cancer therapy.
In some people, it may not be safe to use in conjunction with other cancer treatments.
Echinacea may impair the effectiveness of some chemotherapy medications, including etoposide.
Sometimes pharmacists and medical professionals advise lymphoma patients not to consume echinacea. This is so that it won’t affect how they’re being treated.
Researchers discovered that echinacea and etravine were safe to ingest together in HIV-positive individuals.
If any of the following apply to you before consuming echinacea:
- are breastfeeding or pregnant
- have a medical condition like autoimmune illness, HIV, or AIDS that impairs your immune system
- are medicating to weaken your immune system because it might fight them
- are under 12 years old
- There is a possibility of allergic responses including skin rashes, according to the medical health regulatory association (MHRA).
Always discuss the use of complementary or alternative cancer therapy with your doctors and nurses. They could affect how well your other therapies work.
Your treatment team can point you in the direction of further resources if they don’t have the knowledge you need.
Does echinacea make you feel more tense?
Echinacea can intensify the negative effects of caffeine, including headache, rapid heartbeat, and jitteriness.
Brief overview
However, no studies utilizing Echinacea in the prevention or treatment of illnesses similar to COVID-19 have been found. Current research suggests that echinacea supplementation may reduce the duration and severity of acute respiratory tract infections. There were not many side events reported, indicating the relative safety of this herbal medication. Clinical studies have shown that Echinacea lowers levels of immunological molecules associated with cytokine storm, despite the fact that it might boost immune activity, which raises concerns that it can worsen over-activation of the immune system in cytokine storm.
Verdict
When given at the earliest sign of infection, Echinacea supplements may help with the symptoms of acute respiratory infections (ARI) and the common cold. No trials employing Echinacea in the prevention or treatment of illnesses like COVID-19, however, have been found. When taken at the outset of symptoms, Echinacea may lessen the intensity and/or duration of ARI, according to earlier research. E. purpurea or a mixture of E. purpurea and E. angustifolia having standardized levels of active components were employed in trials claiming benefit.
Echinacea use hasn’t been associated with many side effects, which suggests that this herbal remedy is generally harmless. No human studies using echinacea for up to 4 months could be found that showed cytokine storm symptoms.
The results were largely consistent with a reduction in the pro-inflammatory cytokines that are involved in the progression of cytokine storm and Acute Respiratory Distress Syndrome (ARDS), factors that are highly significant in the death of COVID-19 patients when looking at all human trials that reported changes in cytokine levels in response to Echinacea supplementation. Even though there isn’t any research on the therapeutic benefits of echinacea in the treatment of cytokine storms right now, this evidence shows that more study is necessary.
Caffeine interacts with ECHINACEA
The rate at which the body breaks down caffeine may be slowed by echinacea. When used with coffee, echinacea may raise blood levels of the stimulant and raise the possibility of adverse effects such jitteriness, headaches, and rapid heartbeat.
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with ECHINACEA
The liver modifies and breaks down several drugs. The rate at which the liver breaks down these drugs may change if echinacea is used. The results and side effects of certain drugs may alter as a result.
Medications that decrease the immune system (Immunosuppressants) interacts with ECHINACEA
The immune system’s activity can be boosted by echinacea. Some drugs, such those prescribed after a transplant, reduce the immune system’s function. Echinacea may lessen the effects of several drugs if taken concurrently.
Etoposide (VePesid) interacts with ECHINACEA
Echinacea may slow down the body’s metabolism of etoposide. When used with etoposide, echinacea may make etoposide’s side effects worse.
Midazolam (Versed) interacts with ECHINACEA
The body’s ability to break down midazolam appears to be impacted by echinacea. Echinacea may lessen or intensify the negative effects of midazolam when taken together.
Warfarin (Coumadin) interacts with ECHINACEA
The drug warfarin is used to prevent blood clots. Echinacea may accelerate the breakdown of warfarin and lessen its effectiveness. This could make you more likely to get a clot. Make sure to routinely get your blood tested. Your warfarin dosage may need to be adjusted.
Darunavir (Prezista) interacts with ECHINACEA
Darunavir’s rate of metabolism may be impacted by echinacea. Echinacea may lessen the effects of darunavir or increase the risk of negative effects when taken with it. However, it’s not obvious if this warrants much alarm.
Docetaxel (Taxotere) interacts with ECHINACEA
The rate at which the body breaks down docetaxel may be impacted by echinacea. Echinacea supplementation may lessen the effects of docetaxel or raise the risk of side effects. However, it’s not obvious if this warrants much alarm.
Etravirine (Intelence) interacts with ECHINACEA
The rate at which the body breaks down etravirine may be impacted by echinacea. Echinacea may lessen the effects of etravirine or enhance its negative effects when taken alongside it. However, it’s not obvious if this warrants much alarm.
Lopinavir / Ritonavir (Kaletra) interacts with ECHINACEA
Echinacea may slow down the body’s metabolism of lopinavir and ritonavir. Echinacea can either boost or diminish the effects of lopinavir/ritonavir, depending on whether it is taken alone or in conjunction with it. However, it’s not obvious if this warrants much alarm.
Background
Two prior human studies have shown the echinacea angustifolia extract’s (EP107TM) immediate anxiolytic effects. This investigation’s objectives were to look at echinacea angustifolia’s anxiolytic and mood-lifting effects over a longer period of time with a larger sample size.
Methods
108 individuals with mild-to-moderately severe anxiety were included in this 6-week, 3-arm, parallel-group, double-blind, randomised controlled experiment. They were then randomly assigned to receive either a placebo, 20 mg, or 40 mg of echinacea angustifolia twice daily. Clinically Useful Anxiety Outcome Scale (CUXOS), Positive and Negative Affect Scale (PANAS), Short Form-36 (SF-36), and Bergen Insomnia Scale were some of the outcome measures used (BIS).
Results
Based on information gathered from 104 participants, both echinacea doses were linked to overall decreases in anxiety, even though these effects were comparable to those of a placebo. In contrast to the placebo, both doses of echinacea were linked to higher improvements in the PANAS positive and negative affect scores as well as the SF-36 emotional wellbeing score.
Conclusions
Adults with mild-to-moderately severe anxiety did not experience higher reductions in anxiety when the echinacea angustifolia extract (EP107TM) was given for 6 weeks at doses of 40 and 80 mg daily in comparison to the placebo. However, there were bigger gains in both positive and negative affect, as well as emotional wellness, which may be an impact of antidepressants. Future trials will benefit from more research employing well-defined demographics and established outcome metrics.