What risks are associated with ingesting over-the-counter supplements? I have heard that some supplements can conflict with blood pressure medications because I take them.
Answer:
Yes, what you heard is true. When you have high blood pressure, several nutrients should be avoided. However, early research suggests that in your case, a few vitamins might be helpful.
Despite being marketed as “natural” and not requiring a prescription, supplements can have a variety of negative effects on the body. Supplements can have adverse effects, alter the body’s metabolism, and interfere with drugs. No matter how harmless they may seem, it is generally advised that you see your healthcare physician before taking any supplements.
The following supplements should be on your cautionary list if you have high blood pressure:
- St. John’s wort: This herb is used to treat depression and has the added benefit of accelerating the metabolism of certain drugs. Your blood pressure medicine may be digested so quickly that it no longer has the desired effect. There may be a rise in blood pressure as a result.
- Echinacea: Echinacea is thought to aid with cold and flu symptoms, but some research suggests that it also affects how drugs are digested.
- Ephedra: Due to safety concerns, this substance, which is utilized in weight-loss products, is prohibited in the US. Ephedra has been associated to major health issues such as high blood pressure, heart attacks, strokes, and others.
- Bitter orange: In certain weight-loss products, ephedra left a void that is filled by this supplement. But that does not automatically imply that it is safer. Bitter orange has been associated with strokes and heart attacks and has been shown to raise blood pressure and heart rate.
- Yohimbine: Yohimbine has previously been promoted as a treatment for erectile dysfunction. Its popularity appears to be waning, possibly as a result of numerous negative consequences, such as an increase in blood pressure.
- Ginseng: Early research indicates that ginseng may reduce blood sugar, lessen fatigue, or strengthen the immune system. Additionally, it could change the blood pressure. For people with high or low blood pressure issues, ginseng is best avoided.
Fish oil and garlic are two supplements that have shown some promise in your situation.
According to studies, regularly consuming fatty fish like salmon, tuna, and trout can lower your chance of developing heart disease and passing away. When eating fatty fish twice a week, the heart benefits seem to be the greatest. An alternative for people who can’t or don’t enjoy fish is a fish oil supplement. According to some research, patients with mild hypertension who take a fish oil supplement (4 grams per day) see a slight reduction in blood pressure. However, there is insufficient evidence to fully support fish oil as a method of lowering blood pressure.
Garlic is well known for its possible heart health advantages, particularly for decreasing excessive blood cholesterol levels. Additionally, some data suggests that garlic may loosen blood vessels and smooth muscles. According to studies, ingesting a garlic extract (200–400 mg three times per day for one month) can somewhat lower blood pressure. This research is preliminary and insufficient to support the use of garlic as a sole blood pressure lowering agent.
When treating a medical condition, supplements are never the only option. I hope you and your doctor have also talked about the advantages of a balanced diet, exercise, and stress reduction in addition to medicine. I usually add the following to the list: Find ways to give your life more purpose through your work, relationships, volunteering, or other endeavors. No matter what disease you have, these four strategies form the foundation of excellent health in general.
Do your research when you hear of a fascinating supplement. Finding the research study that might be making headlines is simple thanks to the Internet. Look at the study’s size, if the supplement was put up against a placebo, and the specifics of the findings. Talk to your doctor about how the supplement might influence your health after gathering this information.
Echinacea and blood pressure medications are compatible, right?
There is no proof that echinacea would interact with diuretics, although several natural items, such as Siberian ginseng, St. Mary’s thistle, and grapefruit juice, have been reported to interfere with various types of blood-pressure medication.
What supplements should someone with high blood pressure stay away from?
Examples of herbal supplements that may interfere with blood pressure drugs or your blood pressure are as follows:
- Arnica (Arnica montana)
- Ephedra (ma-huang)
- Ginseng (Panax quinquefolius and Panax ginseng)
- Guarana (Paullinia cupana)
- Licorice (Glycyrrhiza glabra)
What might cause blood pressure to spike suddenly?
Stress. High stress levels might cause a brief rise in blood pressure. Stress-related behaviors like eating more, smoking, or drinking alcohol can cause blood pressure to rise even more. a few enduring conditions.
In whom should echinacea not be taken?
Consult your doctor before using echinacea if you regularly take other medications. Additionally, if you smoke, use illegal substances, drink alcohol or caffeine-containing beverages, you should disclose this to your doctor. These might impact how echinacea functions.
If you have an autoimmune ailment (like lupus), an infection with the human immunodeficiency virus (HIV), or acquired immunodeficiency syndrome, echinacea may not be beneficial to you (AIDS). Before beginning to use echinacea, you should discuss with your doctor if you are pregnant or nursing.
Echinacea allergy risk may be increased if you have a history of allergies to daisies, ragweed, marigolds, chrysanthemums, or other related plants.
Does echinacea make you heart beat faster?
Echinacea can intensify the negative effects of caffeine, including headache, rapid heartbeat, and jitteriness.
Which herb should a person with high blood pressure not consume?
Ephedra is a plant that thrives in dry and semi-arid areas of the world. It is famous for its potentially harmful side effects, which in rare instances may include:
- Strokes
- Seizures
- cardiac arrests
The herb raises blood pressure and quickens heartbeat, particularly if caffeine-containing ephedra is consumed. For weight loss, these herbal supplements are frequently utilized. Ephedra has been demonstrated to significantly raise blood pressure and heart rate when consumed in amounts of 150mg.
For those with high blood pressure, avoiding caffeine and any kind of fat-burning supplement is recommended. Making wiser food and dietary decisions can significantly affect blood pressure control.
St. John’s Wort
Although St. John’s Wort has been linked to certain serious adverse effects and potentially harmful drug interactions, the herb may be beneficial for some people. Notably, studies have indicated that St. John’s Wort raises blood pressure.
St. John’s Wort may interact with several blood pressure drugs, reducing their effectiveness, according to studies. St. John’s Wort should not be taken by anyone using blood pressure medication or dealing with hypertension unless specifically advised to by a medical professional.
Sodium
A mineral called sodium can be present in several multivitamins. It is therefore listed even if it is not exactly one of the vitamins to avoid with high blood pressure because it is crucial to be aware of. Numerous meals include sodium, which is necessary for the health of the nerves and muscles.
High blood pressure is correlated with a salt surplus. Reducing intake can assist lower blood pressure and enhance vascular health.
For the majority of patients with high blood pressure, sodium intake of less than 1,500 mg per day is adequate. Greater salt intake can cause water retention, which is known to strain the heart and blood vessels more.
Today’s world of highly processed meals makes it normal to consume too much sodium. There are 2,400 mg of sodium in just one teaspoon of salt. Instead, stay away from table salt and choose low- or no-sodium foods. Miso paste, which has a similar flavor to salt but less sodium, is a fantastic substitute.
While there are few vitamins that people with high blood pressure should avoid, there are numerous herbs and minerals. Nitric oxide levels can be safely increased through the use of natural food supplements, such as red spinach or beetroot supplements.
American prevalence of hypertension | Million Hearts (2021, March 22). Department of Health and Human Services. https://millionhearts.hhs.gov/data-reports/hypertension-prevalence.html
Which vitamin causes elevated blood pressure?
- A B vitamin called riboflavin supports various metabolic and antioxidant processes and aids in the conversion of food into usable energy.
- Riboflavin assists the MTHFR enzyme by converting folate into the form needed for homocysteine to be converted to methionine.
- A riboflavin deficit may slow the conversion of homocysteine to methionine, and a high blood homocysteine level is linked to a higher risk of hypertension.
- People who have a particular genetic variation (polymorphism) in MTHFR may be more prone to high blood pressure.
- Supplementing with riboflavin reduces blood pressure and homocysteine levels in hypertensive people with the MTHFR c.677C>T polymorphism (homozygotes).
Genetic analysis is used to measure the MTHFR polymorphism. A little bit of blood, saliva, or tissue is used in a genetic test to isolate and identify a person’s genetic information. Genetic testing is optional, and doctors and genetic counselors can help you make that decision.
How can I instantly lower my blood pressure?
Call 9-1-1 right away if you’re attempting to quickly drop your blood pressure at home. Dangerously high blood pressure cannot be safely treated at home. The best course of action is to lay down flat and be quiet until help arrives.
Does water help to reduce blood pressure?
To stay properly hydrated throughout the day, water consumption is advised. It can aid in lubricating the body, lowering the chance of illnesses like kidney stones and urinary tract infections, and it can help improve brain function in addition to lowering blood pressure.
Echinacea in COVID-19
Echinacea appears to be effective against COVID-19 due to its antiviral and immunomodulatory properties [13, 26]. Echinacea has been studied for its potential to treat and prevent respiratory tract infections like the common cold, but not for other medical conditions [27]. Echinacea and COVID-19 have not yet been the subject of any investigations [28]. The safe and efficient use of echinacea in the treatment or prevention of viral infections was determined by a meta-analysis of 17 clinical trials. Echinacea was found to enhance or not modify anti-inflammatory or immune-stimulatory cytokines, while decreasing or not changing pro-inflammatory cytokines linked to cytokine storm (IL-6, IL-1, and TNF-). This analysis involved 12 clinical trials (IL-10, IL-2, IL-8, IL-3, and IFN-). Since immune stimulatory and anti-inflammatory actions are required during infections yet pro-inflammatory cytokines might worsen the condition, these effects are advantageous. The most often reported adverse effects were insomnia, digestive problems, and anxiety. There was one case of severe erythema recorded. It is challenging to assess the safety of echinacea in patients with comorbidities because the majority of trials only involved healthy volunteers and the dose and extraction method were quite diverse [28].
Echinacea in diabetes
The effects of echinacea on diabetes haven’t been the subject of many investigations. 33 days of echinacea root extract in Wistar rats demonstrated hypoglycemic efficacy comparable to glibenclamide. There was no research done on safety parameters [29]. The activities of -amylase, -glucosidase, and ACE were decreased by echinacea purpureaflower extract and caffeic acid derivatives in a concentration-dependent manner [30].
Echinacea in heart disease
The impact of echinacea on cardiac diseases including hypertension and hypercholesterolemia has seldom ever been investigated. In a study with 374 older participants, 349 reported using over-the-counter medications, whereas 43 reported using herbal remedies. Aspirin, acetaminophen, laxatives, antiacids, and vitamins were the most often used over-the-counter medications, whereas echinacea was the most popular herbal treatment [31]. The possibility of echinacea interacting with medications is suggested by this one study.
Echinacea toxicity
Echinacea was rated as having good or medium levels of evidence for its safety and efficacy in a review article [32]. It is debatable if echinacea use for longer than 8 weeks causes hepatotoxicity [6]. Echinacea, on the other hand, has been demonstrated to protect the liver and kidneys from toxins in rats while having no effect on the liver and kidney markers AST, ALT, ALP, blood urea nitrogen, and creatinine [33]. After giving Echinacea purpurea to rats and mice at high dosages orally or intravenously, no harmful effects were noticed. There is no proof that hamster embryonic cells are carcinogenic or mutagenic in mice or in vitro [34]. Echinacea should not be used by people who have autoimmune diseases. There is not enough data to determine how echinacea affects renal impairment [35].
Echinacea pharmacokinetics
Echinacea purpurearoot inhibited CYP1A2 and increased CYP3A enzymes in 12 healthy men and women when tested in vivo [36]. Echinacea purpurea increased CYP3A enzymes in a separate research with 13 healthy people, but it had no effect on the pharmacokinetics of ritonavir. Since ritonavir inhibits CYP3A, it probably prevented the induction brought on by echinacea. P-glycoprotein was not affected [37]. Echinacea purpurea revealed conflicting results on CYP3A4 and a little suppression of CYP2C9 in an in vitro research [38]. Echinacea has a significant likelihood of drug-herb interactions, according to a review article [39].
Echinacea safety summary
When consumed by healthy individuals for a brief period of time—up to 8 weeks—echinacea is probably safe. Patients with diabetes or heart problems are unknown to be safe. When combined with drugs metabolized by CYP3A, 1A2, and 2C9 enzymes, caution should be exercised.
What negative effects can echinacea have?
The more frequent echinacea adverse effects are as follows:
- headaches
- dizziness
- feeling unwell
- belly pain
- constipation
- skin repercussions (redness, itchiness and swelling)
- Children are more likely to have them.
Echinacea use for longer than 8 weeks at a time may cause liver damage or immune system suppression. If you are taking medications known to have an adverse effect on your liver, herbalists advise against taking echinacea.
If you use any additional medications, herbs, or supplements, check with your doctor first.
Using echinacea safely
If you want to substitute echinacea for your cancer therapy, let your doctor know. Additionally, if you are considering taking it concurrently with your cancer therapy.
In some people, it may not be safe to use in conjunction with other cancer treatments.
Echinacea may impair the effectiveness of some chemotherapy medications, including etoposide.
Sometimes pharmacists and medical professionals advise lymphoma patients not to consume echinacea. This is so that it won’t affect how they’re being treated.
Researchers discovered that echinacea and etravine were safe to ingest together in HIV-positive individuals.
If any of the following apply to you before consuming echinacea:
- are breastfeeding or pregnant
- have a medical condition like autoimmune illness, HIV, or AIDS that impairs your immune system
- are medicating to weaken your immune system because it might fight them
- are under 12 years old
- There is a possibility of allergic responses including skin rashes, according to the medical health regulatory association (MHRA).
Always discuss the use of complementary or alternative cancer therapy with your doctors and nurses. They could affect how well your other therapies work.
Your treatment team can point you in the direction of further resources if they don’t have the knowledge you need.